BAPX1 polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254433
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development; homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.
Alternate Names: Homeobox protein Nkx-3.2, NKH3-2, NKX3B, SMMD
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_001180
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human BAPX1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development; homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.
Alternate Names: Homeobox protein Nkx-3.2, NKH3-2, NKX3B, SMMD
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_001180
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human BAPX1.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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