BARK1 / GRK2 polyclonal, anti-human

Background:
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Other Names:
Beta-adrenergic receptor kinase 1, Beta-ARK-1, 2.7.11.15, G-protein coupled receptor kinase 2, ADRBK1, BARK, BARK1, GRK2

Antigen Types:
Synthetic Peptide

Gene Name:
GRK2 (HGNC:289)
Gene ID:
156
Primary Accession: P25098
Other Accession: NP_001610;156;110355 (mouse);