BATF3 Blocking Peptide (Center)

Background:
AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.

Other Names:
Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, Jun dimerization protein p21SNFT, BATF3, SNFT

Target/Specificity:
The synthetic peptide sequence is selected from aa 78-89 of HUMAN BATF3

Gene Name: BATF3

Gene ID: 55509
Primary Accession: Q9NR55
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.