Bax (Apoptosis Marker) (clone SPM336 ), anti-human, primate
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In stock
SKU
AC-AH10705
Catalog Number: AC-AH10705
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM336
Applications: WB, IHC-P, IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM336
Applications: WB, IHC-P, IF, FC
Datasheet
Request Information
Background:
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Other Names:
Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4
Gene Name: BAX
Gene ID: 581
Primary Accession: Q07812
Other Accession: 581, 624291
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Other Names:
Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4
Gene Name: BAX
Gene ID: 581
Primary Accession: Q07812
Other Accession: 581, 624291
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