BAX polyclonal (N-term), anti-human
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In stock
SKU
AC-AP13211a
Catalog Number: AC-AP13211a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32989
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32989
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Other Names:
Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4
Target/Specificity:
This BAX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human BAX.
Antigen Region:
28-56
Antigen Type: Synthetic Peptide
Gene Name: BAX
Gene ID: 581
Primary Accession: Q07812
NCBI Accession: NP_004315.1;NP_620116.1;NP_620118.1;NP_620119.2
Other Accession: NP_004315.1;NP_620118.1;NP_620119.2;NP_620116.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Other Names:
Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4, BAX, BCL2L4
Target/Specificity:
This BAX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human BAX.
Antigen Region:
28-56
Antigen Type: Synthetic Peptide
Gene Name: BAX
Gene ID: 581
Primary Accession: Q07812
NCBI Accession: NP_004315.1;NP_620116.1;NP_620118.1;NP_620119.2
Other Accession: NP_004315.1;NP_620118.1;NP_620119.2;NP_620116.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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