Nectin 3 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73444
Background:
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis- mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Other Names:
PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD113
Antigen Type: synthetic peptide
Antigen Type: NECTIN3 (HGNC:17664)
Gene ID: 25945
Primary Accession: Q9NQS3
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis- mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Other Names:
PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD113
Antigen Type: synthetic peptide
Antigen Type: NECTIN3 (HGNC:17664)
Gene ID: 25945
Primary Accession: Q9NQS3
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