BCAR3 antibody (clone 3G4), anti-human
€435.00
In stock
SKU
AC-AT1278a
Catalog Number: AC-AT1278a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT1278a">Request Information
Background:
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
Other Names:
Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B, BCAR3, NSP2, SH2D3B
Antigen Type:
Recombinant Protein
Gene Name: BCAR3
Gene ID: 8412
NCBI Accession: NP_001248337.1;NP_001248338.1;NP_001248339.1;NP_003558.1
Primary Accession: O75815
Other Accession: BC039895
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
Other Names:
Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B, BCAR3, NSP2, SH2D3B
Antigen Type:
Recombinant Protein
Gene Name: BCAR3
Gene ID: 8412
NCBI Accession: NP_001248337.1;NP_001248338.1;NP_001248339.1;NP_003558.1
Primary Accession: O75815
Other Accession: BC039895
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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