BCAS4 Polyclonal Antibody

Background:
The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer.The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells. Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies.

Research Area: Cancer

Synonyms:
BCAS4, BCAS4/BCAS3 fusion, BCAS4, Breast carcinoma amplified sequence 4, Breast carcinoma amplified sequence 4/3 fusion protein, Breast carcinoma-amplified sequence 4, CNOL, FLJ20495, RP5-1071L10.2

Immunogen: Synthetic peptide of human BCAS4

Swissprot: Q8TDM0
Gene Accession: NP_001010974

Calculated MW: 23 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-85293/sc-85295