BCAT1 Polyclonal Antibody

Background:
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Research Area: Metabolism, Signal Transduction

Synonyms:
BCAT, BCAT(c), Bcat1, BCAT1, BCT1, Branched chain amino acid aminotransferase, cytosolic, branched chain amino-acid transaminase 1, cytosolic, branched chain aminotransferase 1, branched chain aminotransferase 1, cytosolic, Branched-chain-amino-acid aminotransferase, cytosolic, DKFZp686E12175, EC 2.6.1.42, ECA39, MECA39, placental protein 18, PNAS 121, PP18, Protein ECA39

Immunogen: Recombinant protein of human BCAT1

Swissprot: P54687
Gene Accession: NP_005495

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-68655