BCHE Polyclonal Antibody

Background:
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Research Area: Metabolism, Neuroscience, Signal transduction

Synonyms:
Acylcholine acylhydrolase, BCHE, Butyrylcholine esterase, CHE1, CHE2, CHLE, Choline esterase II, Cholinesterase (serum) 2, Cholinesterase 1, Cholinesterase, E1, Pseudocholinesterase, Pseudocholinesterase E1

Immunogen: Fusion protein of human BCHE

Swissprot: P06276
Gene Accession: BC008396

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.