Bcl-2 Antibody (BH3 Domain Specific) Blocking peptide
€363.00
In stock
SKU
AC-BP1303a
Background:
BCL2 is integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Other Names:
Apoptosis regulator Bcl-2, BCL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1303a was selected from the region of human Bcl-2 BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BCL2
Gene ID: 596
Primary Accession: P10415
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
BCL2 is integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Other Names:
Apoptosis regulator Bcl-2, BCL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1303a was selected from the region of human Bcl-2 BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BCL2
Gene ID: 596
Primary Accession: P10415
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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