Bcl-2 monoclonal, anti-human, mouse
€455.00
In stock
SKU
AC-ABO13757
Catalog Number: AC-ABO13757
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, FC
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, FC
Datasheet
Request Information
Description: Anti-Bcl-2 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.
Protein Function:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1)..
Other Names: Apoptosis regulator Bcl-2, BCL2
Clone Name(s):
Clone: AAOH-2
Subcellular Localization: Mitochondrion outer membrane ; Single-pass membrane protein. Nucleus membrane ; Single-pass membrane protein. Endoplasmic reticulum membrane ; Single-pass membrane protein.
Tissue Specificity: Expressed in a variety of tissues.
Gene ID: 596
Immunogen: A synthesized peptide derived from human Bcl-2
Calculated MW: 26266
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1)..
Other Names: Apoptosis regulator Bcl-2, BCL2
Clone Name(s):
Clone: AAOH-2
Subcellular Localization: Mitochondrion outer membrane ; Single-pass membrane protein. Nucleus membrane ; Single-pass membrane protein. Endoplasmic reticulum membrane ; Single-pass membrane protein.
Tissue Specificity: Expressed in a variety of tissues.
Gene ID: 596
Immunogen: A synthesized peptide derived from human Bcl-2
Calculated MW: 26266
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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