Bcl-2 (phospho-Thr56) polyclonal, anti-human antibody
€315.00
In stock
SKU
AC-ABV11671-100
Catalog Number: AC-ABV11671-100
Size: 100 µl
Host: Rabbit IgG
Applications: WB, IHC, IF, E, IP
Datasheet
Request Information
Size: 100 µl
Host: Rabbit IgG
Applications: WB, IHC, IF, E, IP
Datasheet
Request Information
Background:
The Bcl-2 family of proteins is the best characterized protein family involved in the regulation of apoptotic cell death in variety of cells. Bcl2 is an integral outer mitochondrial membrane protein that regulates mitochondrial calcium homeostasis and proton flux. Several reports suggested that these phosphorylation sites may be targets of the ASK1/MKK7/JNK1 pathway and that phosphorylation of Bcl-2 may be a marker for mitotic events. Mutation of Bcl-2 at Thr56 or S87 inhibits its anti-apoptotic activity during glucocorticoid-induced apoptosis of T lymphocytes.
Other Names:
BCL2, Apoptosis regulator Bcl-2
Primary Accession: P10415
Gene Name: BCL2
Gene ID: 596
Concentration (mg/ml): 1mg/ml
The Bcl-2 family of proteins is the best characterized protein family involved in the regulation of apoptotic cell death in variety of cells. Bcl2 is an integral outer mitochondrial membrane protein that regulates mitochondrial calcium homeostasis and proton flux. Several reports suggested that these phosphorylation sites may be targets of the ASK1/MKK7/JNK1 pathway and that phosphorylation of Bcl-2 may be a marker for mitotic events. Mutation of Bcl-2 at Thr56 or S87 inhibits its anti-apoptotic activity during glucocorticoid-induced apoptosis of T lymphocytes.
Other Names:
BCL2, Apoptosis regulator Bcl-2
Primary Accession: P10415
Gene Name: BCL2
Gene ID: 596
Concentration (mg/ml): 1mg/ml
| Is Featured? | No |
|---|
Write Your Own Review