Bcl-2 polyclonal (Center Ser70), anti-human

Bcl-2 polyclonal (Center Ser70), anti-human

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In stock
SKU
AC-AP20322c
Catalog Number: AC-AP20322c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42026
Applications: WB
Datasheet

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Background:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Other Names:
Apoptosis regulator Bcl-2, BCL2

Target/Specificity:
This Bcl-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-76 amino acids from the Central region of human Bcl-2.

Antigen Region:
49-76

Antigen Type: Synthetic Peptide

Gene Name: BCL2
Gene ID: 596
Primary Accession: P10415
NCBI Accession: NP_000624.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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