Bcl-w polyclonal (BH3 Domain Specific), anti-human, mouse
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In stock
SKU
AC-AP1305a
Catalog Number: AC-AP1305a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0972
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0972
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Other Names:
Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W, BCL2L2, BCLW, KIAA0271
Target/Specificity:
This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-59 amino acids from human Bcl.
Antigen Region:
24-59
Antigen Type: Synthetic Peptide
Gene Name: BCL2L2
Gene ID: 599
Primary Accession: Q92843
NCBI Accession: NP_001186768.1;NP_004041.1
Other Accession: P70345; Q1RMX3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Other Names:
Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W, BCL2L2, BCLW, KIAA0271
Target/Specificity:
This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-59 amino acids from human Bcl.
Antigen Region:
24-59
Antigen Type: Synthetic Peptide
Gene Name: BCL2L2
Gene ID: 599
Primary Accession: Q92843
NCBI Accession: NP_001186768.1;NP_004041.1
Other Accession: P70345; Q1RMX3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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