BCL11A antibody (clone 3D9), anti-human
€435.00
In stock
SKU
AC-AT1281a
Catalog Number: AC-AT1281a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT1281a">Request Information
Background:
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
Other Names:
B-cell lymphoma/leukemia 11A, BCL-11A, B-cell CLL/lymphoma 11A, COUP-TF-interacting protein 1, Ecotropic viral integration site 9 protein homolog, EVI-9, Zinc finger protein 856, BCL11A, CTIP1, EVI9, KIAA1809, ZNF856
Antigen Type:
Recombinant Protein
Gene Name: BCL11A
Gene ID: 53335
NCBI Accession: NP_060484.2;NP_075044.2;NP_612569.1
Primary Accession: Q9H165
Other Accession: NM_018014
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
Other Names:
B-cell lymphoma/leukemia 11A, BCL-11A, B-cell CLL/lymphoma 11A, COUP-TF-interacting protein 1, Ecotropic viral integration site 9 protein homolog, EVI-9, Zinc finger protein 856, BCL11A, CTIP1, EVI9, KIAA1809, ZNF856
Antigen Type:
Recombinant Protein
Gene Name: BCL11A
Gene ID: 53335
NCBI Accession: NP_060484.2;NP_075044.2;NP_612569.1
Primary Accession: Q9H165
Other Accession: NM_018014
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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