BCL2 Monoclonal Antibody
€0.00
In stock
SKU
E-AB-22004
Catalog Number: E-AB-22004
Isotype: Mouse IgG, Clone: 1B3
Reactivity: human, mouse, rat
Applications: WB,IHC-p
Datasheet, Questions? Contact us!
Isotype: Mouse IgG, Clone: 1B3
Reactivity: human, mouse, rat
Applications: WB,IHC-p
Datasheet, Questions? Contact us!
Background:
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction
Synonyms:
Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, Bcl-2, Bcl2, BCL2, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, B-cell, 2, Oncogene B-cell leukemia 2, PPP1R50, Protein phosphatase 1, regulatory subunit 50
Immunogen: Synthetic Peptide
Swissprot: P10415
Calculated MW: 26 kDa
Observed MW: 26 kDa
Purification Method: Protein A purification
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration: 1 mg/mL
Dilution: WB 1:1000-2000, IHC 1:50-1:200
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Alternative for product with catalog number:
sc-783/sc-492
Citation(s):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296/
https://pubmed.ncbi.nlm.nih.gov/32179202/
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction
Synonyms:
Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, Bcl-2, Bcl2, BCL2, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, B-cell, 2, Oncogene B-cell leukemia 2, PPP1R50, Protein phosphatase 1, regulatory subunit 50
Immunogen: Synthetic Peptide
Swissprot: P10415
Calculated MW: 26 kDa
Observed MW: 26 kDa
Purification Method: Protein A purification
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration: 1 mg/mL
Dilution: WB 1:1000-2000, IHC 1:50-1:200
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Alternative for product with catalog number:
sc-783/sc-492
Citation(s):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390296/
https://pubmed.ncbi.nlm.nih.gov/32179202/
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