BCL2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Synonyms: Bcl-2, PPP1R50

Cellular Location: Endoplasmic reticulum membrane Mitochondrion outer membrane Nucleus membrane Single-pass membrane protein

Immunogen:
A synthetic peptide of human BCL2

Gene Symbol: BCL2

Gene ID: 596

Swiss prot: P10415

Calculated MW: 26kDa

Recommended dilution:
WB 1:500-1000, IHC 1:50-100, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.