BCL2L1 polyclonal (C-term), anti-human, rat

Background:
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(S) promotes apoptosis.

Other Names:
Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCL2L1, BCL2L, BCLX

Target/Specificity:
This BCL2L1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 195-229 amino acids from the C-terminal region of human BCL2L1.

Gene Name: BCL2L1
Gene ID: 598
Primary Accession: Q07817
Other Accession: P53563; O77737; Q64373
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.