BCL2L2 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.

Synonyms: BCLW, BCL-W, PPP1R51, BCL2-L-2

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human BCL2L2

Gene Symbol: BCL2L2

Gene ID: 599

Swiss prot: Q92843

Calculated MW: 21kDa

Recommended dilution:
WB 1:500-2000, IHC 1:30-150,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.