Bcl3 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

Description:
Rabbit IgG polyclonal antibody for B-cell lymphoma 3 protein (BCL3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
B cell CLL/lymphoma 3 antibody, B cell leukemia/lymphoma 3 antibody, B cell lymphoma 3 encoded protein antibody, B-cell lymphoma 3 protein antibody, Bcl 3 antibody, BCL 4 antibody, BCL-3 antibody, Bcl3 antibody, BCL3_HUMAN antibody, BCL4 antibody, Chronic lymphatic leukemia protein antibody, D19S37 antibody, Protein Bcl 3 antibody, Proto-oncogene BCL3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Bcl3(199-216aa MALDRHGQTAAHLACEHR), different from the related rat and mouse sequences by one amino acid.A synthetic peptide corresponding to a sequence in the middle region of human Bcl3(199-216aa MALDRHGQTAAHLACEHR), different from the related rat and mouse sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.