BCL6 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Synonyms: BCL5, BCL6A, LAZ3, ZBTB27, ZNF51

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human BCL6

Gene Symbol: BCL6

Gene ID: 604

Swiss prot: P41182

Calculated MW: 79kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.