BCL6 polyclonal (C-term), anti-human

Background:
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Other Names:
B-cell lymphoma 6 protein, BCL-6, B-cell lymphoma 5 protein, BCL-5, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51, BCL6, BCL5, LAZ3, ZBTB27, ZNF51

Target/Specificity:
This BCL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 676-704 amino acids from the C-terminal region of human BCL6.

Antigen Region:
676-704

Antigen Type: Synthetic Peptide

Gene Name: BCL6
Gene ID: 604
Primary Accession: P41182
NCBI Accession: NP_001124317.1;NP_001128210.1;NP_001697.2
Other Accession: NP_001128210.1;NP_001124317.1;NP_001697.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.