BCOR Antibody (Center S1122) Blocking Peptide

Background:
BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.

Other Names:
BCL-6 corepressor, BCoR, BCOR, KIAA1575

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7359c was selected from the Center region of human BCOR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: BCOR

Gene ID: 54880
Primary Accession: Q6W2J9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.