BCRP/ABCG2 polyclonal, anti-mouse, rat
€455.00
In stock
SKU
AC-ABO11177
Catalog Number: AC-ABO11177
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µg
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Description: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 2(ABCG2) detection. Tested with WB in Mouse;Rat.Protein Name: ATP-binding cassette sub-family G member 2
Protein Function:
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain (By similarity). May play a role in early stem cell self-renewal by blocking differentiation. .
Other Names: ATP-binding cassette sub-family G member 2, Breast cancer resistance protein 1 homolog, Urate exporter, CD338, Abcg2, Abcp, Bcrp1
Subcellular Localization: Cell membrane ; Multi-pass membrane protein . Mitochondrion membrane ; Multi-pass membrane protein .
Tissue Specificity: Highly expressed in kidney. Lower expression in liver, colon, heart, spleen, and placenta. .
Gene ID: 26357
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse BCRP/ABCG2(152-167aa KNHEKNERINTIIKEL), different from the related rat sequence by one amino acid.
Calculated MW: 72978
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain (By similarity). May play a role in early stem cell self-renewal by blocking differentiation. .
Other Names: ATP-binding cassette sub-family G member 2, Breast cancer resistance protein 1 homolog, Urate exporter, CD338, Abcg2, Abcp, Bcrp1
Subcellular Localization: Cell membrane ; Multi-pass membrane protein . Mitochondrion membrane ; Multi-pass membrane protein .
Tissue Specificity: Highly expressed in kidney. Lower expression in liver, colon, heart, spleen, and placenta. .
Gene ID: 26357
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse BCRP/ABCG2(152-167aa KNHEKNERINTIIKEL), different from the related rat sequence by one amino acid.
Calculated MW: 72978
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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