BDNF polyclonal, anti-human, mouse, rat

Background:
Brain-derived neurotrophic factor, also known as BDNF, is a member of the "neurotrophin" family of growth factors, which are related to the canonical "Nerve Growth Factor", NGF. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. BDNF is actually found in a range of tissue and cell types, not just in the brain. It is also expressed in the retina, the central nervous system, motor neurons, the kidneys, and the prostate. Various studies have shown possible links between BDNF and conditions such as depression, bipolar disorder,schizophrenia, obsessive-compulsive disorder, Alzheimer's disease, Huntington's disease, Rett syndrome, and dementia, as well as anorexia nervosa and bulimia nervosa.

Alternative Name:
BDNF, Abrineurin, ANON2, BDNF, BDNF, Brain Derived Neurotrophic Factor, Brain-derived neurotrophic factor, BULN2, MGC34632, Neurotrophin,

Application Dilution:
WB:1:500
ICC:1:200
IHC:1:200

Specificity: BDNF polyclonal antibody detects endogenous levels of BDNF protein.

Immunogen:
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to the N-terminal of human BNDF

MW: 28kDa

Swiss-Prot: P23560(Human) P21237(Mouse) P23363(Rat)

Purification & Purity:
Peptide affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.