Beclin 1 polyclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AP1818a
Catalog Number: AC-AP1818a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7461
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7461
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis. Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.
Other Names:
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, BECN1, GT197
Target/Specificity:
This Beclin 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from human Beclin 1.
Antigen Region:
181-210
Antigen Type: Synthetic Peptide
Gene Name: BECN1
Gene ID: 8678
Primary Accession: Q14457
NCBI Accession: NP_003757.1
Other Accession: Q5ZKS6; Q4A1L4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Beclin 1 plays a role in two fundamentally important cell biological pathways: autophagy and apoptosis. Beclin 1 is thought to function as a VPS and autophagy protein as part of a complex with Class III PI3 kinase, Vps34.
Other Names:
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, BECN1, GT197
Target/Specificity:
This Beclin 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-210 amino acids from human Beclin 1.
Antigen Region:
181-210
Antigen Type: Synthetic Peptide
Gene Name: BECN1
Gene ID: 8678
Primary Accession: Q14457
NCBI Accession: NP_003757.1
Other Accession: Q5ZKS6; Q4A1L4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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