BECN1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Synonyms: ATG6, VPS30, beclin1

Cellular Location: Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum membrane Endosome Endosome membrane Golgi apparatus Mitochondrion Mitochondrion membrane Nucleus Peripheral membrane protein autophagosome trans-Golgi network membrane

Immunogen:
Recombinant protein of human BECN1

Gene Symbol: BECN1

Gene ID: 8678

Swiss prot: Q14457

Calculated MW: 52kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.