BECN1 Polyclonal Antibody

Background:
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Microbiology, Signal Transduction

Synonyms:
ATG6, VPS30, beclin1, Beclin 1, BECN1, beclin-1

Immunogen: Recombinant fusion protein of human BECN1 (NP_003757.1).

Swissprot: Q14457
Gene ID: 8678

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.