BEST3 polyclonal (N-term), anti-human
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In stock
SKU
AC-AP19190a
Catalog Number: AC-AP19190a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39849
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39849
Applications: WB
Datasheet
Request Information
Background:
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes,BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).
Other Names:
Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3, BEST3, VMD2L3
Target/Specificity:
This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3.
Antigen Region:
40-68
Antigen Type: Synthetic Peptide
Gene Name: BEST3 (HGNC:17105)
Gene ID: 144453
Primary Accession: Q8N1M1
NCBI Accession: NP_116124.2;NP_689652.2
Other Accession: NP_116124.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes,BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).
Other Names:
Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3, BEST3, VMD2L3
Target/Specificity:
This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3.
Antigen Region:
40-68
Antigen Type: Synthetic Peptide
Gene Name: BEST3 (HGNC:17105)
Gene ID: 144453
Primary Accession: Q8N1M1
NCBI Accession: NP_116124.2;NP_689652.2
Other Accession: NP_116124.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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