Beta-2 Microglobulin (Renal Failure & Tumor Marker) (clone SPM374), anti-human

Beta-2 Microglobulin (Renal Failure & Tumor Marker) (clone SPM374), anti-human

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In stock
SKU
ARP-24-567-MSM1X
Catalog Number: 24-567-MSM1X
Size: 100 µl, 0.5 ml, 1 ml
Isotype: Mouse IgG2a, kappa
Decription:
Recognizes a protein of 12kDa, identified as ļ� �ļ€ �ļ€ �microglobulin. Beta-ļ€ �-microglobulin non-covalently associates with the 44kDa ļ�� chain to form the HLA Class I antigen complex. Humanļ€ļ� �eta-ļ€ �-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This monoclonal antibody is specific to humanļ€ļ� �ļ€ �-microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Ć�2Āmicroglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.

Synonyms: B2M, Beta 2 microglobin, Beta 2 microglobulin, Beta chain of MHC class I molecules, Beta-2-microglobulin form pI 5.3, Hdcma22p

Clone: SPM374

Isotype: Mouse IgG2a, kappa

Immunogen: Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient

Reactivity: human. Does not react with non-human primates. Others not known.

Form: Purified, in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (0.5-1ug/ml)
Optimal dilution for a specific application should be determined.

Reactivity: HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.

Concentration: 0.2mg/ml

Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
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