beta-Actin (clone AC-15), anti-human, mouse, rat

beta-Actin (clone AC-15), anti-human, mouse, rat

€354.00
In stock
SKU
ARP-10-M1115
Catalog Number: 10-M1115
Size: 100 µg
Isotype: Mouse IgG1
Background:
The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al.(1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.

Decription:
Mouse IgG monoclonal antibody for beta-Actin, actin, beta (ACTB) detection. Tested with WB, IHC-P in Human, mouse, rat. No cross reactivity with other proteins.

Synonyms: BRWS1, PS1TP5BP1, BETA-ACTIN, ACTIN, CYTOPLASMIC, 1

Clone: AC-15

Isotype: Mouse IgG1

Immunogen: slightly modified beta-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH.

Reactivity: human, mouse, rat

Form: Lyophilized; Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Applications: WB, IHC-P

Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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