Beta Amyloid polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
beta Amyloid, also called Abeta or Abeta, denotes peptides of 36–43 amino acidsthat are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. It is mapped to 19q13.12. Several potential activities have been discovered for beta Amyloid, including activation of kinase enzymes, functioning as atranscription factor, and anti-microbial activity (potentially associated with beta Amyloid's pro-inflammatoryactivity). Moreover, monomeric beta Amyloid is indicated to protect neurons by quenching metal-inducible oxygen radical generation and thereby inhibiting neurotoxicity.

Description:
Rabbit IgG polyclonal antibody for Amyloid beta A4 protein (APP) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
A4 antibody, A4 antibody, A4_HUMAN antibody, AAA antibody, AAA antibody, ABETA antibody, ABETA antibody, ABPP antibody, ABPP antibody, AD1 antibody, AICD-50 antibody, AICD-57 antibody, AICD-59 antibody, AID(50) antibody, AID(57) antibody, AID(59) antibody, Alzheimer disease amyloid protein antibody, Alzheimers Disease Amyloid Protein antibody, Amyloid B antibody, amyloid beta (A4) precursor protein antibody, amyloid beta A4 protein antibody, Amyloid Beta A4 Protein Precursor antibody, Amyloid Beta antibody, Amyloid intracellular domain 50 antibody, Amyloid intracellular domain 57 antibody, Amyloid intracellular domain 59 antibody, Amyloid of Aging and Alzheimer Disease antibody, APP antibody, APPI antibody, APPI antibody, B Amyloid antibody, Beta APP antibody, beta-amyloid peptide antibody, Beta-APP40 antibody, Beta-APP42 antibody, C31 antibody, Cerebral Vascular Amyloid Peptide antibody, CTFgamma antibody, CVAP antibody, CVAP antibody, Gamma-CTF(50)antibody, Gamma-CTF(57) antibody, Gamma-CTF(59) antibody, peptidase nexin-II antibody, PN II antibody, PN-II antibody, PN2 antibody, PreA4 antibody, PreA4 antibody, Protease nexin II antibody, Protease nexin-II antibody, S-APP-alpha antibody, S-APP-beta antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human beta Amyloid(672-713aa DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA), different from the related mouse and rat sequences by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.