Beta-Pix polyclonal, anti-human, mouse, rat

Quantity: 100 µl

Description:
beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.

Synonyms:
Rho Guanine Nucleotide Exchange Factor 7, PAK-interacting Exchange Factor beta, p85SPR, COOL-1

Isotype: Rabbit Polyclonal

Immunogen:
Recombinant beta-Pix SH3 domain.

Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Specificity:
Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms. Cross-reacts with human and rat beta-Pix.

Reactivity: human, mouse, rat

Applications: ELISA, Immunocytochemistry, Western Blot

Working DIlution: Optimal conditions must be determined individually for each application.

Storage: 2-8C immediate use, or -20C (aliquoted)