BGLAP polyclonal, anti-human,mouse

Background:
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

Synonyms: BGP, OC, OCN, osteocalcin

Cellular Location: Secreted

Immunogen:
A synthetic peptide of human BGLAP

Gene Symbol: BGLAP

Gene ID: 632

Swiss prot: P02818

Calculated MW: 11kDa

Recommended dilution:
WB 1:500-1:2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.