BHMT2 Polyclonal Antibody

Background:
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms:
Betaine homocysteine methyltransferase 2, Betaine homocysteine S methyltransferase 2, EC 2.1.1.5, FLJ20001 , S methylmethionine homocysteine S methyltransferase BHMT2, SMM hcy methyltransferase

Immunogen: Fusion protein of human BHMT2

Swissprot: Q9H2M3
Gene Accession: BC020665

Calculated MW: 40 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.