Bi-Phospho-LLGL1/2(S655/659) /(S645/S649) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP2198a
Background:
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
Other Names:
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2198a was selected from the region of human Phospho-LLGL1/2-S650/S654. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LLGL2
Gene ID: 3993
Primary Accession: Q6P1M3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
Other Names:
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2198a was selected from the region of human Phospho-LLGL1/2-S650/S654. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LLGL2
Gene ID: 3993
Primary Accession: Q6P1M3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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