Bi-Phospho-LLGL1/2(S655/659) /(S645/S649) polyclonal, anti-human
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In stock
SKU
AC-AP2198a
Catalog Number: AC-AP2198a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7629;RB7630
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7629;RB7630
Applications: WB
Datasheet
Request Information
Background:
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
Other Names:
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Target/Specificity:
This LLGL1/2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S645/S649 of human LLGL1/2.
Antigen Type: Synthetic Peptide
Primary Accession: Q15334, Q6P1M3
NCBI Accession: NP_001015002.1;NP_001026973.1;NP_004515.2
Other Accession: Q3TJ91; Q8K4K5; Q80Y17; Q15334; Q8MKF0; Q6P1M3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
Other Names:
Lethal(2) giant larvae protein homolog 2, HGL, LLGL2
Target/Specificity:
This LLGL1/2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S645/S649 of human LLGL1/2.
Antigen Type: Synthetic Peptide
Primary Accession: Q15334, Q6P1M3
NCBI Accession: NP_001015002.1;NP_001026973.1;NP_004515.2
Other Accession: Q3TJ91; Q8K4K5; Q80Y17; Q15334; Q8MKF0; Q6P1M3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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