Bi-Phospho-MEK1/2(S218/222) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3158a
Background:
MEK1 and MEK2 are members of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. These protein kinases lie upstream of MAP kinases and stimulate the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. They are essential components of the MAP kinase signal transduction pathway. These kinases are involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Other Names:
Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K1, MEK1, PRKMK1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3158a was selected from the region of human Phospho-MEK1/2-S218/222. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAP2K1 (HGNC:6840)
Gene ID: 5604
Primary Accession: Q02750
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MEK1 and MEK2 are members of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. These protein kinases lie upstream of MAP kinases and stimulate the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. They are essential components of the MAP kinase signal transduction pathway. These kinases are involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Other Names:
Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K1, MEK1, PRKMK1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3158a was selected from the region of human Phospho-MEK1/2-S218/222. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAP2K1 (HGNC:6840)
Gene ID: 5604
Primary Accession: Q02750
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review