Bi-Phospho-MEK1(S218/222) polyclonal, anti-human
€0.00
In stock
SKU
AC-AP3159a
Catalog Number: AC-AP3159a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB05985
Applications: IHC-P, DB, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB05985
Applications: IHC-P, DB, WB
Datasheet
Request Information
Background:
MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Other Names:
Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K1, MEK1, PRKMK1
Target/Specificity:
This MEK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S218/222 of human MEK1.
Antigen Type: Synthetic Peptide
Gene Name: MAP2K1 (HGNC:6840)
Gene ID: 5604
Primary Accession: Q02750
NCBI Accession: NP_002746.1
Other Accession: P36506; Q63932; P36507; Q90891; Q05116; Q01986; P29678; P31938; Q63980; Q10664; Q24324
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Other Names:
Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K1, MEK1, PRKMK1
Target/Specificity:
This MEK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S218/222 of human MEK1.
Antigen Type: Synthetic Peptide
Gene Name: MAP2K1 (HGNC:6840)
Gene ID: 5604
Primary Accession: Q02750
NCBI Accession: NP_002746.1
Other Accession: P36506; Q63932; P36507; Q90891; Q05116; Q01986; P29678; P31938; Q63980; Q10664; Q24324
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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