Bid polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
BID(BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2 family of proteins consists of both antagonists and agonists that regulate apoptosis and compete through dimerization. By fluorescence in situ hybridization, Wang et al.(1998) mapped the human BID gene to 22q11. Luo et al.(1998) reported the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as FAS and TNF.

Description:
Rabbit IgG polyclonal antibody for BH3-interacting domain death agonist (Bid) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
Apoptic death agonist antibody, Apoptotic death agonist antibody, Apoptotic death agonist BID antibody, BH3 interacting domain death agonist antibody, BH3 interacting domain death agonist p11 antibody, BH3 interacting domain death agonist p13 antibody, BH3 interacting domain death agonist p15 antibody, BH3-interacting domain death agonist p11 antibody, BID antibody, BID isoform ES(1b) antibody, BID isoform L(2) antibody, BID isoform Si6 antibody, BID_HUMAN antibody, Desmocollin type 4 antibody, FP497 antibody, HGNC:1050 antibody, Human BID coding sequence antibody, MGC15319 antibody, MGC42355 antibody, p11 BID antibody, p13 BID antibody, p15 BID antibody, p22 BID antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bid(179-195aa NQNLFSYVRNLVRNEMD), different from the related rat sequence by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bid(179-195aa NQNLFSYVRNLVRNEMD), different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.