Bik BH3 Domain Antibody Blocking Peptide
€363.00
In stock
SKU
AC-BP1319a
Background:
The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Other Names:
Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4, BIK, NBK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1319a was selected from the region of human Bik BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BIK {ECO:0000303|PubMed:7478623, ECO:0000312|HGNC:HGNC:1051}
Gene ID: 638
Primary Accession: Q13323
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Other Names:
Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4, BIK, NBK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1319a was selected from the region of human Bik BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BIK {ECO:0000303|PubMed:7478623, ECO:0000312|HGNC:HGNC:1051}
Gene ID: 638
Primary Accession: Q13323
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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