Bik BH3 Domain polyclonal, anti-human
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In stock
SKU
AC-AP1319a
Catalog Number: AC-AP1319a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3381
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB3381
Applications: WB, IHC-P
Datasheet
Request Information
Background:
The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Other Names:
Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4, BIK, NBK
Target/Specificity:
This Bik BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-74 amino acids from human Bik BH3 Domain.
Antigen Region:
39-74
Antigen Type: Synthetic Peptide
Gene Name: BIK {ECO:0000303|PubMed:7478623, ECO:0000312|HGNC:HGNC:1051}
Gene ID: 638
Primary Accession: Q13323
NCBI Accession: NP_001188.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Other Names:
Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4, BIK, NBK
Target/Specificity:
This Bik BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-74 amino acids from human Bik BH3 Domain.
Antigen Region:
39-74
Antigen Type: Synthetic Peptide
Gene Name: BIK {ECO:0000303|PubMed:7478623, ECO:0000312|HGNC:HGNC:1051}
Gene ID: 638
Primary Accession: Q13323
NCBI Accession: NP_001188.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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