Bik polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. This gene is mapped to 22q13.31. The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Description:
Rabbit IgG polyclonal antibody for Bcl-2-interacting killer (BIK) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Apoptosis inducer NBK antibody, BBC1 antibody, Bcl-2-interacting killer antibody, BCL2 interacting killer antibody, bhikhari antibody, BIK antibody, Bik-like killer protein antibody, BIK_HUMAN antibody, BIP 1 antibody, BiP1 antibody, BP 4 antibody, BP4 antibody, cb 60 antibody, NBK antibody.

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Bik recombinant protein (Position: M1-R123). Human Bik shares 42.3% amino acid (aa) sequence identity with mouse Bik.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.