BIN1 (clone 99D), anti-human, mouse, rat
€354.00
In stock
SKU
ARP-10-M1005
Catalog Number: 10-M1005
Size: 100 µg
Isotype: Mouse IgG2b
Size: 100 µg
Isotype: Mouse IgG2b
Background:
BIN1(AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.
Decription:
Mouse IgG monoclonal antibody for BIN1, bridging integrator 1 (BIN1) detection. Tested with WB, IHC-F, ICC in Human, mouse, rat. No cross reactivity with other proteins.
Synonyms: AMPHL, AMPH2, SH3P9, amphiphysin II, Amphiphysin-like protein;Box-dependent myc-interacting protein 1;Bridging integrator 1
Clone: 99D
Isotype: Mouse IgG2b
Immunogen: Recombinant polypeptide containing amino acids 189-398 of human Bin1.
Reactivity: human, mouse, rat
Form: Lyophilized; Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Applications: WB, IHC-F, ICC
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
BIN1(AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.
Decription:
Mouse IgG monoclonal antibody for BIN1, bridging integrator 1 (BIN1) detection. Tested with WB, IHC-F, ICC in Human, mouse, rat. No cross reactivity with other proteins.
Synonyms: AMPHL, AMPH2, SH3P9, amphiphysin II, Amphiphysin-like protein;Box-dependent myc-interacting protein 1;Bridging integrator 1
Clone: 99D
Isotype: Mouse IgG2b
Immunogen: Recombinant polypeptide containing amino acids 189-398 of human Bin1.
Reactivity: human, mouse, rat
Form: Lyophilized; Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Applications: WB, IHC-F, ICC
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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