BIRC5 antibody (clone 5B10), anti-human
€435.00
In stock
SKU
AC-AT1299a
Catalog Number: AC-AT1299a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, IP, E
Request Information AC-AT1299a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, IP, E
Request Information AC-AT1299a">Request Information
Background:
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Other Names:
Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, API4, IAP4
Antigen Type:
Recombinant Protein
Gene Name: BIRC5
Gene ID: 332
NCBI Accession: NP_001012270.1;NP_001012271.1;NP_001159.2
Primary Accession: O15392
Other Accession: NM_001168
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Other Names:
Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, API4, IAP4
Antigen Type:
Recombinant Protein
Gene Name: BIRC5
Gene ID: 332
NCBI Accession: NP_001012270.1;NP_001012271.1;NP_001159.2
Primary Accession: O15392
Other Accession: NM_001168
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review