BIRC6 polyclonal (C-Term), anti-human
€0.00
In stock
SKU
AC-AP22251b
Catalog Number: AC-AP22251b
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB56699
Applications: WB, FC
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB56699
Applications: WB, FC
Datasheet
Request Information
Background:
Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.
Other Names:
Baculoviral IAP repeat-containing protein 6, 6.3.2.-, BIR repeat-containing ubiquitin-conjugating enzyme, BRUCE, Ubiquitin-conjugating BIR domain enzyme apollon, APOLLON, BIRC6, KIAA1289
Target/Specificity:
This BIRC6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 4810-4844 amino acids from human BIRC6.
Antigen Type: Synthesized Peptide
Gene Name: BIRC6
Gene ID: 57448
Primary Accession: Q9NR09
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.
Other Names:
Baculoviral IAP repeat-containing protein 6, 6.3.2.-, BIR repeat-containing ubiquitin-conjugating enzyme, BRUCE, Ubiquitin-conjugating BIR domain enzyme apollon, APOLLON, BIRC6, KIAA1289
Target/Specificity:
This BIRC6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 4810-4844 amino acids from human BIRC6.
Antigen Type: Synthesized Peptide
Gene Name: BIRC6
Gene ID: 57448
Primary Accession: Q9NR09
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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