BIRC7 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants

Synonyms: KIAP, LIVIN, ML-IAP, MLIAP, RNF50

Cellular Location: Cytoplasm Golgi apparatus Nucleus

Immunogen:
Recombinant protein of human BIRC7

Gene Symbol: BIRC7

Gene ID: 79444

Swiss prot: Q96CA5

Calculated MW: 33kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.