Bisphosphate 3'-nucleotidase polyclonal, anti-human

Background:
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Other Names:
3'(2'),5'-bisphosphate nucleotidase 1, 3.1.3.7, Bisphosphate 3'-nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP, BPNT1

Antigen Types:
Synthetic Peptide

Gene Name:
BPNT1
Gene ID:
10380
Primary Accession: O95861
Other Accession: NP_006076;10380;23827 (mouse); 64473 (rat);