Bmf BH3 Domain polyclonal, anti-human
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In stock
SKU
AC-AP1309a
Catalog Number: AC-AP1309a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB00594
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB00594
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Bmf belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis.
Other Names:
Bcl-2-modifying factor, BMF
Target/Specificity:
This Bmf BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-150 amino acids from human Bmf BH3 Domain.
Antigen Region:
115-150
Antigen Type: Synthetic Peptide
Gene Name: BMF
Gene ID: 90427
Primary Accession: Q96LC9
NCBI Accession: NP_001003940.1;NP_001003942.1;NP_001003943.1;NP_277038.1
Other Accession: Q91ZE9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Bmf belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis.
Other Names:
Bcl-2-modifying factor, BMF
Target/Specificity:
This Bmf BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-150 amino acids from human Bmf BH3 Domain.
Antigen Region:
115-150
Antigen Type: Synthetic Peptide
Gene Name: BMF
Gene ID: 90427
Primary Accession: Q96LC9
NCBI Accession: NP_001003940.1;NP_001003942.1;NP_001003943.1;NP_277038.1
Other Accession: Q91ZE9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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